Samuel Rund joined the centre in April 2014
Biological clocks (“circadian rhythms”) underlie diverse bio logical processes including detoxification, metabolism, sensory processes, and immunity. These rhythms allow organisms to adjust to an environment that can change dramatically over the 24 hour day. Disruption (such as “jet-lag”) of these rhythms has serious consequences to the organism; and there are, for example, time-of-day specific effects to drug efficacy and insecticide toxicity.
My present work focuses on understanding how daily biological rhythms function and interact in the context of disease and disease transmission, particularly in insect-transmitted diseases. Disruption or exploitation of natural rhythms in the host, vector, or even pathogen could lead to novel disease interventions.
Additionally, I continue to investigate the basic physiolo gy and behavior of the mosquito.
West Mains Road,